Medicines that are certified safe and have expired patents Cheap price, accessible everywhere. It appears that it has properties other than what was previously known and is used in a different context. It is something that should be paid attention to in being a repurpose drug and also traditional Thai herbal medicine and Eastern medicine. Including other treatment methods should be open-minded and studied seriously. And finally, it can be used together with modern western medicine, such as the parasitic drug ivermectin. Satoshi ōmura and William C. Campbell won the Nobel Prize in Physiology and Internal Medicine in 2015 for their discovery. It is a very effective drug in treating various parasitic diseases and has saved many lives in Africa. During the following period, the effects and mechanisms of this drug were studied. Until it was discovered that this drug had properties to stop infection. Including the treatment of viral infections, especially those in the RNA group, such as the Covid virus, until it was used on many continents. In India, Africa, even in Japan. England and the United States, however, were fiercely opposed and censored and doctors’ licenses revoked. And the US federal agency FDA has made some cynical remarks. But ultimately lost the case to the United States Supreme Court. Let the reproach be removed. Messages in all media that slanders such parasitic drugs and the doctor won the case Thursday evening, March 21, 2024, was an unprecedented court case. The court ruled in favor of the US FDA, led by cardiologist Robert Califf. Dismantle all false and misleading claims about ivermectin. This medicine is part of the community standard use of care for COVID-19. It has an excellent safety record and evidence of benefit in no less than 101 studies…during 2021, what is called “War on Ivermectin” US FDA posts false and misleading tweets and sending public messages to dissuade doctors, pharmacists, and patients from using the drug. and as a result, the doctor who prescribed it was ordered to stop working. withdraw license And it led to a lawsuit, which the FDA ultimately lost, pre-COVID. Period of outbreak And after the outbreak subsided, there was interest in the mechanism by which this parasitic drug could act against many types of cancer. both in terms of suppressing growth spread and inhibits the creation of blood vessels that feed various cancer tumors This also includes light installments. The situation of resistance of various types of cancer to treatment and chemotherapy. and are used in combination to control cancer better. Important mechanisms that have already been studied is the ability to cause cancer to die through processes called programmed cell death, autophagy, and pyroptosis through the PAK1 kinase pathway, among others. The aim of studying this drug in cancer is to help it be combined with chemotherapy drugs to provide Even more effective, for example, some articles study this drug in various types of cancer, such as breast cancer, especially in the group called triple negative, where there is no estrogen, progesterone receptor and human epidermal growth factor receptors 2 (HER2) and cancer. that grows and spreads fastest Ivermectin acts as an epigetic regulator and also makes this type of cancer respond to the normal drug tamoxifen… Several studies have also found that ivermectin Helps make cancer cells die better by adjusting the tumor microenvironment by releasing high mobility group box-1 protein (HMGB1), causing immune cell reactions that cause inflammation and cell death. cancer In gastric cancer, ivormectin was found to be able to inhibit cell growth through Yes-associated protein 1 (YAP1) and this process is also used to explain the effect on liver cancer. bile duct cancer And the drug also helps cancers that are resistant to gemcitabine, a chemotherapy drug used to treat colon cancer that causes cell death in the process of apoptosis by blocking the Wnt/beta catenin pathway. It also has an effect in cases of kidney cancer (renal cell carcinoma) by Does not affect normal cells This is by obstructing the duties of The drug also appears to help prostate cancer by enhancing the effects of the anti-androgen drug enzalutamide and re-enacting docetaxel-resistant cancer cells…leukemia. Drugs that kill cancer in a dose that is not high and does not affect normal cells This is by inducing free radicals. and has an effect on promoting the action of the drugs cytarabine and daunorubicin. In addition, it is effective on non-acute cancers, chronic myeloid leukemia, and helps improve the work of the drug dasatinib…cervical cancer and ovarian cancer. Drugs also help make chemotherapy more effective. In brain tumors, drugs help treat glioblastoma through mechanisms that cause cell death and inhibit the formation of blood vessels to supply the tumor and the spread of cancer cells. However, Iverme Cytin does not cross the blood-brain barrier well, so this may limit its use in brain tumors unless it can sufficiently open the hole or gap in the barrier without this occurring. Permanently… nasopharyngeal cancer, lung cancer, and melanoma. This drug can help standard treatments become more effective. The attached link describes the drug’s efficacy and mechanism. to various types of cancer tumors, such as Nature 2021 journal https://www.nature.com/articles/s41523-021-00229-5 Nature 2022 journal https://www.nature.com/articles/s4141 9-022-05182-0 and other journals https://www.sciencedirect.com/science/article/pii/S1043661820315152 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505114/ https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2021.71752 9/full https:/ /journals.sagepub.com/doi/full/10.1177/09603271221143693 https://www.mdpi.com/2079-972 1/11/1/49 https://www.frontiersin.org/journals/pharmacology/articles /10.3389/fphar.2022.934746/full https://ar.iiarjournals.org/content/39/9/4837 These are examples of medicines that have many properties. In addition to what was discovered from the beginning and likely reflects the circumstances of hemp and marijuana herbs The family of a patient who has been diagnosed with no cure and only palliative care has used it to relieve the pain and suffering of not being able to sleep or eat. But he was able to live an almost normal life and live with his family, with everyone slowly accepting him. And finally, even if the patient leaves But they did not suffer. These patients were given the painkiller morphine, both oral and injectable, but they were unable to relieve their symptoms. At the same time, there are a large number of cancer patients who have received a confirmed diagnosis of their cancer and even the final stage of its spread… when using hemp. By giving correct and appropriate has returned to live longer than normal as expected from standard treatment. Should I start seriously considering taking various herbs? Including Eastern medicine such as Chinese medicine to study and improve understanding and be able to identify reactions. Including contraindications when used in conjunction with modern medicine. Which one is for the highest benefit of the patient and to save money and allow the sick public to have full access? Doctor Nua click to read the column. More “Happy Health”
